Multiple sclerosis (MS) is a demyelinating and inflammatory disease of the central nervous system (CNS). The de-myelination process can be repaired by the generation of a new sheath of myelin around the axon, a process termed remyelination. In MS patients, the demyelination-remyelination cycles are highly dynamic. Over the years, magnetic...
-
December 2020 (v1)Journal articleUploaded on: December 4, 2022
-
February 20, 2024 (v1)Publication
Multiple sclerosis (MS) is a demyenalinating inflammatory neurological disease. In vivo biomarkers of myelin content are of major importance for patient care and clinical trials. Positron Emission Tomography (PET) with Pittsburgh Compound B (PiB) provides a specific myelin marker. However, it is not available in clinical routine. In this paper,...
Uploaded on: December 29, 2023