En este ciclo de mejora se ha trabajado partiendo de un caso clínico sobre el que han versado todas las cuestiones que conectaban diferentes temas de la asignatura (4 temas concretamente, todos ellos relacionados con el infarto agudo de miocardio). Los alumnos han trabajado en pequeños grupos con diferentes actividades de contraste, dependiendo...
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May 16, 2019 (v1)PublicationUploaded on: March 27, 2023
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May 30, 2018 (v1)Publication
En los últimos años se ha venido desarrollando un especial interés por la evidente relación calcio e hipertensión arterial. Muchos han sido los autores interesados en este tema. La aparición en diversos trabajos, tanto clínicos como experimentales, en que se demuestran niveles más bajos de calcio iónico en sujetos con hipertensión arterial...
Uploaded on: December 4, 2022 -
March 31, 2020 (v1)Publication
La obesidad y la osteoporosis (OP) son dos patologías muy prevalentes en nuestra sociedad actual. El efecto de la obesidad sobre la calidad ósea se encuentra en debate en la actualidad. Objetivo: Valorar el efecto del peso corporal sobre la microestructura y las propiedades biomecánicas de hueso trabecular procedente de biopsias de extremidad...
Uploaded on: March 25, 2023 -
March 31, 2020 (v1)Publication
Valorar niveles séricos de 25-hidroxivitamina D -25(OH)D-, hormonas con influencia sobre el metabolismo óseo (parathormona -PTH- y factor de crecimiento insulínico -IGF-I-), marcadores de remodelado óseo (MRO) (telopéptido carboxilo-terminal del colágeno tipo I -β-CTX- y propéptido aminoterminal del procolágeno tipo I -PINP-), densidad mineral...
Uploaded on: March 27, 2023 -
February 27, 2015 (v1)Publication
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Uploaded on: December 5, 2022 -
June 27, 2019 (v1)Publication
Los micro-ARN (miRs) son pequeñas moléculas de ARN no codificantes que regulan la expresión génica a nivel post-transcripcional. Generalmente actúan sobre la expresión genética mediante el silenciamiento o degradación de los ARNm, y están implicados en la regulación de varios procesos biológicos, como la diferenciación celular, la...
Uploaded on: March 27, 2023 -
July 7, 2021 (v1)Publication
Background: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic fracture. Several factors have been identified as being potentially responsible for this risk, such as alterations in bone remodelling that may have been induced by changes in circulating glucose or/and by the presence of non-oxidative end products...
Uploaded on: December 4, 2022 -
May 12, 2023 (v1)Publication
Objective To evaluate the incidence of osteoporotic hip fracture in the Macarena Health Area (Seville). Setting and participants This was a prospective observational study that collected all osteoporotic hip fractures that occurred between March 2013 and February 2014 at the Clinical Unit of Traumatology and Orthopaedics. All cases collected...
Uploaded on: May 13, 2023 -
May 27, 2021 (v1)Publication
Introducción: La diabetes mellitus (DM) tipo 2 se asocia a un mayor riesgo de fractura osteoporótica. Se han señalado múltiples factores como posibles mecanismos responsables, entre ellos las alteraciones en el remodelado óseo que podrían estar inducidas por las variaciones de glucosa circulante o por la presencia de productos finales de...
Uploaded on: March 25, 2023 -
June 7, 2017 (v1)Publication
The OPG / RANKL system in primary cultures of human osteoblasts has been studied by di ff erent authors. However, very few studies have been performed on gene expression of RANKL and OPG at di ff erent stages of maturation on human osteoblast cultures.The e ff ect of 17-estradiol and 1,25dihydroxyvitamin D3 on the OPG / RANKL system...
Uploaded on: March 27, 2023 -
November 3, 2023 (v1)Publication
Objetivos Los implantes óseos son utilizados cada vez con mayor frecuencia en la práctica clínica y, entre los materiales, el Ti o sus aleaciones son los de mejor rendimiento por sus propiedades fisicoquímicas. Aleaciones como TiNbTa han demostrado mejorar las características biomecánicas del Ti puro comercial (c.p.), sin embargo, su capacidad...
Uploaded on: November 25, 2023 -
May 6, 2021 (v1)Publication
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and it is associated with an increased risk of osteoporosis and fragility fractures. Our aim is to analyze the effect of T2DM on bone quality. This is a case-control study. The studied population consisted of 140 patients: 54 subjects with hip fracture (OP)...
Uploaded on: December 4, 2022 -
June 2, 2020 (v1)Publication
A great variety of powder metallurgy techniques can produce biomimetic porous titanium structures with similar mechanical properties to host bone tissue. In this work, loose sintering and space holder techniques, two frequently used metallurgical techniques, are compared to evaluate the influences of porosity (content, size, morphology and wall...
Uploaded on: March 27, 2023 -
July 5, 2023 (v1)Publication
Circulating osteogenic precursor (COP) cells are peripheral blood cells with a capacity for osteogenesis. The objective of our study was to ascertain the percentage of COPs as an early biomarker of osteoporosis and the effect of these cells in response to Denosumab (DmAb) (anti-resorptive) or to Teriparatide (TPDP) (anabolic) as very effective...
Uploaded on: July 7, 2023 -
September 9, 2020 (v1)Publication
The use of titanium implants with adequate porosity (content, size and morphology) could solve the stress shielding limitations that occur in conventional titanium implants. Experiments to assess the cellular response (adhesion, proliferation and differentiation of osteoblasts) on implants are expensive, time-consuming and delicate. In this...
Uploaded on: March 26, 2023 -
May 21, 2021 (v1)Publication
Fragility fractures constitute a major public health problem worldwide, causing important high morbidity and mortality rates. The aim was to present the epidemiology of fragility fractures and to assess the imminent risk of a subsequent fracture and mortality. This is a retrospective population-based cohort study (n = 1369) with a fragility...
Uploaded on: March 24, 2023 -
October 10, 2022 (v1)Publication
Objectives: To describe the Fracture Liaison Service (FLS), to know the characteristics of the patients attended with emphasis on sex differences, and to know the compliance of International Osteoporosis Foundation (IOF) quality standards. Methods: Observational, prospective research. All the consecutive patients that attended in usual clinical...
Uploaded on: March 24, 2023 -
January 27, 2021 (v1)Publication
In this work, the mechanical and bio-functional behavior of a TiNbTa alloy is evaluated as a potential prosthetic biomaterial used for cortical bone replacement. The results are compared with the reference Ti c.p. used as biomaterials for bone-replacement implants. The estimated mechanical behavior for TiNbTa foams was also compared with the...
Uploaded on: March 27, 2023