YANG , Jing

Spirotetramat is a potent insecticide against plant sapping insects applied worldwide. Once activated in the plant, it targets the first enzyme of the lipid biosynthetic pathway acetyl-CoA decarboxylase. Its impact on target insect survival and fecundity has been studied extensively. Detailed phenotypic analyses of spirotetramat exposure,...

Cuticle barrier efficiency in insects depends largely on cuticular lipids. To learn about the evolution of cuticle barrier function, we compared the basic properties of the cuticle inward and outward barrier function in adults of the fruit flies Drosophila suzukii and Drosophila melanogaster that live on fruits sharing a similar habitat. At low...

Upon uptake of toxins, insects launch a detoxification program. This program is deployed in multiple organs and cells to raise their tolerance against the toxin. The molecular mechanisms of this program inside the insect body have been studied and understood in detail. Here, we report on a yet unexplored extra -corporeal detoxification of...

Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3, little is known about the effect of these modifications on chromatin accessibility, which is fundamental to understand PcG function. Here, by integrating chromatin accessibility, histone marks and...