MAYORAL GONZÁLEZ , Isabel

Las enfermedades cardiovasculares son la principal causa de muerte en el mundo desarrollado, siendo tres de ellas las más prevalentes para ambos sexos; cardiopatía isquémica (13 % de la mortalidad mundial), ictus (12 %) e hipertensión arterial (2 %) (Virani et al., 2020). La primera de ellas, la cardiopatía isquémica es una enfermedad provocada...

Restoration of epicardial coronary blood flow, achieved by early reperfusion with primary percutaneous coronary intervention (PPCI), is the guideline recommended to treat patients with ST-segment-elevation myocardial infarction (STEMI). However, despite successful blood restoration, increasing numbers of patients develop left ventricular...

In-stent restenosis (ISR) is one of the main limitations of percutaneous coronary intervention (PCI) therapy with drug-eluting stents (DES) implantation. The aim of this study was to determine if circulating microRNAs (miRNAs) have diagnostic capability for determining ISR in a cohort of matched patients. Blood samples were collected from 55...

Three-dimensional (3D) engineered cardiovascular tissues have shown great promise to replace damaged structures. Specifically, tissue engineering vascular grafts (TEVG) have the potential to replace biological and synthetic grafts. We aimed to design an in-vitro patient-specific patch based on a hybrid 3D print combined with vascular smooth...