SQUARA , Fabien

Atrial fibrillation (AF) is the most frequent arrhythmia, and is responsible for significant morbidity and mortality. Its interventional treatment requires electrical isolation of the pulmonary veins, and usually additional ablation of specific atrial zones is performed in the setting of persistent AF. Persistent AF ablation based on...

Atrial fibrillation (AF) is a sustained arrhythmia whose mechanisms are still largely unknown. A recent patient-tailored AF ablation therapy is based on the use of a multipolar mapping catheter called PentaRay. This new protocol targets areas of spatiotemporal dispersion (STD) in the atria as potentialAF drivers. However, interventional...

A recent patient-tailored ablation protocol to treat atrial fibrillation consists in identifying ablation sites based on their spatiotemporal dispersion (STD). STD represents a delay of the cardiac activation observed in intracardiac electrograms (EGMs) across contiguous leads. This work aims at automatically identifying ablation sites by...

Atrial fibrillation (AF) is a common heart condition in the elderly, significantly increasing stroke risk and posing a public health concern. Among treatments, catheter ablation (CA) is the most effective long-term solution for persistent AF. A new CA technique targets spatio-temporal dispersion (STD) patterns in intracardiac electrograms...

Atrial fibrillation (AF) is a common cardiac condition that predominantly affects the elderly, posing a significant risk for stroke and raising public health concerns. Catheter ablation (CA) is the most effective long-term treatment for persistent AF. A novel CA approach based on spatio-temporal dispersion (STD) targets active zones that...

Atrial Fibrillation (AF) is the most widespread sustained arrhythmia in clinical practice. A recent personalized AF therapy consists in ablating areas displaying spatiotemporal dispersion (STD) electrograms (EGM) with the use of catheters. Interventional cardiologists use a multipolar mapping catheter called PentaRay to identify visually atrial...

Atrial fibrillation (AF) is a common cardiac condition that predominantly affects the elderly population, presenting a significant risk factor for strokes and thus raising concerns in public health. Catheter ablation (CA) stands out as the most effective long-term treatment for persistent AF. A recently proposed novel CA approach is based on...

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International audience

BackgroundOutcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function andremodeling. We hypothesized that changes in RV function, especially area strain (AS), couldprovide incremental prognostic data.PurposeTo assess global and regional 3D RV function changes between baseline and 6-months visit andevaluate their...

BackgroundOutcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function andremodeling. We hypothesized that changes in RV function, especially area strain (AS), couldprovide incremental prognostic data.PurposeTo assess global and regional 3D RV function changes between baseline and 6-months visit andevaluate their...

Background: Pulmonary embolism (PE) is a common life-threatening disease, with mortality related to right ventricular (RV) dysfunction. Aims: To investigate the value of 3D global and regional right ventricular strain in patients with acute PE and at 1 month, as compared to a control population.Methods and Results: We conducted a longitudinal...

Catheter ablation is increasingly used to treat atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical practice. A recent breakthrough finding in AF ablation consists in identifying ablation sites based on their spatiotemporal dispersion (STD). STD stands for a delay of the cardiac activation observed in...

Background : Outcomes in pulmonary hypertension (PH) are related to right ventricular (RV) function and remodeling. We hypothesized that changes in RV function and especially area strain (AS) could provide incremental prognostic information compared to the use of baseline data only. We therefore aimed to assess RV function changes between...

Background Persistent Atrial Fibrillation (PersAF) electrogram-based ablation is complex, and appropriate identification of atrial substrate is critical. Little is known regarding the value of the Average Complex Interval (ACI) feature for PersAF ablation. Objective Using the evolution of AF complexity by sequentially computing AF dominant...

Background. Fibrillatory Wave Amplitude (FWA) has been described as a non-invasive marker of atrial fibrillation (AF) complexity, and it predicts catheter ablation outcome. However, the actual determinants of FWA remain incompletely understood.Objective. To assess the respective implications of anatomical atrial substrate and AF spectral...

Background: Right ventricular (RV) function assessment is crucial in congenital heart disease (CHD) patients, especially in atrial septal defect (ASD) and repaired Tetralogy of Fallot (TOF) patients with pulmonary regurgitation (PR). In this study, we aimed to analyse both 3D RV shape and deformation to better characterize RV function in ASD...

Background: Survival in pulmonary hypertension (PH) relates to right ventricular (RV) function. However, the RV unique anatomy and structure limit 2D analysis and its regional 3D function has not been studied yet. The aim of this study was to assess the implications of global and regional 3D RV deformation on clinical condition and survival in...

BackgroundRecent literature reports a strong thrombotic tendency in patients hospitalized for a coronavirus disease 2019 (COVID‐19) infection. This characteristic is unusual and seems specific to COVID‐19 infections, especially in their severe form. Viral infections can trigger acquired thrombophilia, which can then lead to thrombotic...

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