YEGOROV , Ivan

For both fundamental biology and engineering applications, it is relevant to investigate how microorganisms adapt to changing environmental conditions. In this work, we consider a continuous-timedynamic problem of resource allocation between metabolic and gene expression machineries for a self-replicating prokaryotic cell population. In...

Understanding adaptation of bacterial growth for a changing environment is a fundamental biological problem which also has a great interest from the biotechnological point of view. This paper extends one of existing bacterial growth models by taking macromolecular degradation into account and provides new mathematical results. The related...

A significant class of plant pathogens is constituted by biotrophic fungi. They set up long-term feeding relationships with their hosts. This kind of parasitism decreases competitive abilities of plants in natural environments and reduces yields in agricultural systems. Therefore, it is relevant to develop and validate mathematical models which...

Microorganisms have evolved complex strategies for controlling the distribution of available resources over cellular functions. Biotechnology aims at interfering with these strategies, so as to optimize the production of metabo-lites and other compounds of interest, by (re)engineering the underlying regulatory networks of the cell. The...

This paper studies a zero-sum state-feedback game for a system of nonlinear ordinary differential equations describing one-seasonal dynamics of two biotrophic fungal cohorts within a common host plant. From the perspective of Adaptive Dynamics, the cohorts can be interpreted as resident and mutant populations. The invasion functional takes the...

The growth of microorganisms is controlled by strategies for the dynamical allocation of available resources over different cellular functions. Synthetic biology approaches are considered nowadays to artificially modify these strategies and turn microbial populations into biotechnological factories for the production of metabolites of interest....

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