YÚFERA GARCÍA , Alberto

En este trabajo de Tesis se demuestra la realización de FDO mediante técnicas de corrientes conmutadas, SI, en el marco de tecnologías VLSI CMOS digitales. La organización y contenido de esta memoria se puede resumir de la siguiente forma.En el Capítulo 2 se hace una breve revisión sobre los conceptos fundamentales de la teoría de FDO,...

This paper presents a computer tool for automatic analysis of cell culture images. The program allows the extraction of relevant information from biological images for pre and post system analysis. In particular, this tool is being used for electrical characterization of electrode-solution-cell systems in which bio-impedance is the main...

Se presenta un paquete de software didáctico que facilita el proceso de enseñanza/aprendizaje de la electrónica, orientado a un sistema de adquisición de datos elemental. Consta de una breve sección expositiva, en la que se describen los contenidos de la materia, más un conjunto de simulaciones que permiten al alumno conocer el funcionamiento...

This paper presents a computer tool for automatic analysis of cell culture images. The program allows the extraction of relevant information from biological images for pre and post system analysis. In particular, this tool is being used for electrical characterization of electrode-solution-cell systems in which bio-impedance is the main...

A sinusoidal voltage wave generator is proposed based on the use of micro- processor digital signals with programmable duty-cycles, with application to real-time Electrical Cell-substrate Impedance Spectroscopy (ECIS) assays in cell cultures. The working principle relies on the time convolution of the programmed microcontroller (μC) digital...

It is proposed a microscopy for cell culture applications based on impedance sensors. The imagined signals are measured with the Electrical Cell-Substrate Spectroscopy (ECIS) technique, by identifying the cell area. The proposed microscopy allows real-time monitoring inside the incubator, reducing the contamination risk by human manipulation....

This paper proposes a new method for bio-impedance measurement useful to 2D processing of cell cultures. It allows to represent biological samples by using a new impedance sensing method, and exploiting the electrode-to-cell model for both electrical simulation and imaging reconstruction. Preliminary electrical simulations are reported to...

The implementation of a continuous-time filter (CTF) useful for audio frequency applications is presented in this paper. The filter functions can be programmed and tuned with two independent control variables. The filter here proposed has been designed to work at 1.5 V of power supply and at a maximum of 0.5 /spl mu/A/OTA for the worst case...

This paper proposes a method for impedance measurements based on a closed-loop implementation of CMOS circuits. The proposed system has been conceived for alternate current excited systems, performing simultaneously driving and measuring functions, thanks to feedback. The system delivers magnitude and phase signals independently, which can be...

Se presenta un entorno de programación para el estudio y desarrollo de algoritmos de tratamiento de imágenes y visión por computador. La herramienta permite la programación en cualquier lenguaje, con la única restricción de que se desarrolle bajo entornos windows. Se ha concebido como instrumento de ayuda a la realización de prácticas de...

Se presenta un entorno de programación para el estudio y desarrollo de algoritmos de tratamiento de imágenes y visión por computador. La herramienta permite la programación en cualquier lenguaje, con la única restricción de que se desarrolle bajo entornos windows. Se ha concebido como instrumento de ayuda a la realización de prácticas de...

Se presenta un paquete de software didáctico que facilita el proceso de enseñanza/ aprendizaje de la electrónica, en concreto, de convertidores digital-analógicos. Consta de una sección expositiva, en la que se describen los contenidos de la materia, más un conjunto de simulaciones que permiten al alumno conocer el funcionamiento interno del...

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High-throughput data analysis challenges in laboratory automation and lab-on-a-chip devices' applications are continuously increasing. In cell culture monitoring, specifically, the electrical cell-substrate impedance sensing technique (ECIS), has been extensively used for a wide variety of applications. One of the main drawbacks of ECIS is the...

This paper presents a capacitive system capable of performing leg volume change monitorization in patients suffering from Heart Failure (HF) conditions. The body volume evolution serves as a prognosis marker for this kind of patients, such patients can benefit from a wearable monitorization system. The proposal is based on a contactless...

Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability of bioimpedance sensing to detect the...

This paper proposes the application of a cell-microelectrode model in cell biometry experiments, using the cell-electrode area overlap as its main parameter. The model can be applied to cell size identification and cell count, and further extended to study cell growth and dosimetry protocols. Experiments have been conducted in AA8 cell line,...

This paper presents a new low voltage/low power filter design based on Floating-Gate MOS (FGMOS) transistors. FGMOS transistors are used as primitives to design linear and non-linear (/spl radic/x) circuits. This technique enables a voltage reduction in strong inversion mode, and gives a new vision of the translinear principle, suitable for low...

In this paper, a CMOS implementation of a low voltage micropower logarithmic biquad based on floating gate MOS transistors (FGMOS) is presented. The translinear principle applied to the floating gate MOS transistor leads to an easy implementation of the state-space equations without using the source terminal in the loop. The voltage supply can...

This paper proposes a cell-microelectrode model for cell biometry applications, based on the area overlap as main parameter. The model can be applied to cell size identification, cell count, and their extension to cell growth and dosimetry protocols. Experiments performed with comercial electrodes are presented, illustrating a procedure to...

In this paper, an incremental Analog-to- Digital Converter (ADC) designed as part of the signalconditioning circuitry for tissue impedance measurement system is presented. Continuous-time design techniques has been used and a modified implementation of the conversion algorithm, with respect to its discrete-time counterpart, has been developed....

A second-order gm-C filter based on the Floating-Gate MOS (FGMOS) technique is presented. It uses a new fully differential transconductor and works at 2 V of voltage supply with a full differential input linear range and a THD below 1%. Programming and tuning are performed by means of a single voltage signal. The transconductor incorporates a...