Diffusion Magnetic Resonance Imaging (dMRI) is the only non-invasive and in-vivo imaging modality able to provide human brain structural connectivity information. This is done via an estimation of the fiber orientation distribution (FOD) of white matter and dMRI tractography. In this thesis, three-dimensional Polarized Light Imaging (3D-PLI) is...
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May 27, 2020 (v1)PublicationUploaded on: December 4, 2022
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May 11, 2019 (v1)Conference paper
Three-dimensional Polarized Light Imaging (3D-PLI) is an optical approach presented as a good candidate for validation of diffusion Magnetic Resonance Imaging (dMRI) results such as orientation estimates (fiber Orientation Distribution Functions) and tractography. We developed an anlytical approach to reconstruct fiber ODFs from 3D-PLI...
Uploaded on: December 4, 2022 -
September 20, 2018 (v1)Conference paper
Non-invasive estimation of brain white matter microstructure features using diffusion MRI - otherwise known as Microstructure Imaging - has become an increasingly diverse and complicated field over the last decade. Multi-compartment-based models have been a popular approach to estimate these features. In this work, we present Diffusion...
Uploaded on: December 4, 2022 -
August 8, 2020 (v1)Conference paper
The in vivo validation of diffusion MRI (dMRI)-based tractography has beenshown to be a challenging task [Maier-hein et al.]. Therefore, we have been investigating how 3D Polarized Light Imaging (3D-PLI) could be used as a validation tool for dMRI-based fiber orientation estimation and tractography. PLI is an optical imaging technique that...
Uploaded on: December 4, 2022 -
September 27, 2021 (v1)Conference paper
Diffusion Magnetic Resonance Imaging (dMRI) is a powerful non-invasive and in-vivo imaging modality for probing brain white matter structure. Convolutional neural networks (CNNs) have been shown to be a powerful tool for many computer vision problems where the signals are acquired on a regular grid and where translational invariance is...
Uploaded on: December 4, 2022 -
April 4, 2018 (v1)Conference paper
Three dimensional polarized light imaging (3D-PLI) utilizes the birefringence in postmortem tissue to map its spatial fiber structure at a submillimeter resolution. We propose an analytical method to compute the fiber orientation distribution function (ODF) from high-resolution vector data provided by 3D-PLI. This strategy enables the bridging...
Uploaded on: February 28, 2023 -
November 20, 2019 (v1)Conference paper
International audience
Uploaded on: December 4, 2022 -
April 8, 2019 (v1)Conference paper
Three dimensional Polarized Light Imaging (3D-PLI) allows to map the spatial fiber structure of postmortem tissue at a sub-millimeter resolution, thanks to its birefringence property. Different methods have been recently proposed to reconstruct the fiber orientation distribution function (fODF) from high-resolution vector data provided by...
Uploaded on: December 4, 2022 -
October 2020 (v1)Journal article
Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to compute the fiber orientation distribution (FOD) from high-resolution vector data provided by 3D-PLI. The...
Uploaded on: December 4, 2022 -
June 16, 2018 (v1)Publication
Synopsis We study the sensitivity of time-dependent diffusion MRI indices or qτ-indices to demyelination in the mouse brain. For this, we acquire in vivo four-dimentional diffusion-weighted images-varying over gradient strength, direction and diffusion time-and estimate the qτ-indices from the corpus callosum. First order Taylor approximation...
Uploaded on: February 28, 2023 -
October 15, 2021 (v1)Journal article
Diffusion MRI (dMRI) has become an invaluable tool to assess the microstructural organization of brain tissue. Depending on the specific acquisition settings, the dMRI signal encodes specific properties of the underlying diffusion process. In the last two decades, several signal representations have been proposed to fit the dMRI signal and...
Uploaded on: December 4, 2022